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Criteria for a recommended standard... occupational exposure to o-tolidine.

Authors
NIOSH
Source
NIOSH 1978 Aug; :1-77
NIOSHTIC No.
00094156
Abstract
A method is described for the sampling and analysis of o-tolidine (119937) , based on a method successfully used for benzidine (92875). Air is drawn through a two stage sampler consisting of a high efficiency fiber filter and a silica gel bed which collects o- tolidine and its salts. The filter and sorbent sections of the sampler are transferred to stoppered tubes and the o-tolidine is desorbed. A triethylamine/methyl-alcohol solution is injected into a high pressure liquid chromatograph. Peak readings are obtained and compared with a standard calibration curve. This method can detect 0.15 to 6.5 micrograms of benzidine per sample (3 to 130 micrograms per cubic meter for a 50 liter air sample) using 0.5 milliliters of desorbing solution and a 10 microliter injection into the liquid chromatograph. The authors suggest that the range of detection for o-tolidine should be similar to that for benzidine. The limit of detection for o-tolidine is predicted to be about 0.05 micrograms per sample.
Keywords
NIOSH-Criteria-Document; Sampling-methods; Filters; Measurement-methods; Measurement-instrumentation; Industrial-organic-chemicals; Standards; Work-environment; Amines
CAS No.
119-93-7; 92-87-5
Publication Date
19780801
Document Type
Numbered Publication; Criteria Document
Funding Type
Contract
Fiscal Year
1978
NTIS Accession No.
PB81-227084
NTIS Price
A01
Identifying No.
(NIOSH) 78-179; Contract-099-74-0031
Source Name
NIOSH, Cincinnati, Ohio
State
OH
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