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Histopathologic classification of bronchogenic carcinomas among a cohort of workers occupationally exposed to beryllium.

Authors
Smith-AB; Suzuki-Y
Source
Environ Res 1980 Feb; 21(1):10-14
NIOSHTIC No.
00093491
Abstract
Pathology reports and specimens of 27 respiratory cancer victims were examined. The subjects had been occupationally exposed to beryllium (7440417) for an undetermined length of time. Microscope slides of tumor specimens were reviewed, tumor histology was classified, and smoking histories were determined from clinical records. In 25 of the cases, the primary site of malignancy was the lung: five of these malignancies were epidermoid carcinomas; nine were small cell anaplastic carcinomas; six were adenocarcinoma, bronchogenic type; two were adenocarcinoma, bronchiolar alveolar type; and three were large cell undifferentiated carcinomas. Among the 25 lung cancer patients, 17 were smokers at the time of hospitalization or were former smokers. The authors conclude that their evidence is insufficient to define the types of specific tumors associated with beryllium exposure.
Keywords
NIOSH-Author; Respiratory-system-disorders; Carcinogenesis; Mortality-data; Statistical-analysis; Metallic-poisons; Air-contamination
CODEN
ENVRAL
CAS No.
7440-41-7
Publication Date
19800201
Document Type
Journal Article
Fiscal Year
1980
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
0013-9351
NIOSH Division
DSHEFS
Priority Area
Respiratory-system-disorders
Source Name
Environmental Research
State
OH
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