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Argyria: clinical implications of exposure to silver nitrate and silver oxide.

Authors
Rosenman-KD; Moss-A; Kon-S
Source
J Occup Med 1979 Jun; 21(6):430-435
NIOSHTIC No.
00091945
Abstract
A physical examination, an opthalmological study, pulmonary function tests, chest x-rays for workers over 40, five questionnaires, and laboratory tests were performed on thirty employees from a small manufacturing facility in New York to determine the effects of exposure to silver-nitrate (7761888) and silver-oxide (1301968). Air sampling was done 4 months prior to examination. Silver-oxide concentrations were above the OSHA standard of 0.01 milligrams per cubic meter. Argyrosis was identified in 20 individuals, and 6 also had generalized argyria. Five of these six had been employed for more than 10 years. Abdominal pain was associated with the presence of silver in blood. Complaints of decreased night vision correlated with increased duration of employment and presence and degree of silver deposited in the cornea. The authors conclude that argyria was generally benign, but the permanent discoloration of the skin and eyes and effect on night vision were sufficient reasons to limit silver exposure. Monitoring of silver in air concentrations and periodic slit lamp examinations are suggested as helpful ways to assess the concentration of silver in the body.
Keywords
JOCMA7; NIOSH-Publication; NIOSH-Grant; Dermatitis; Silver-poisoning; Metal-poisoning; Skin-disorders; Medical-examinations; X-ray-diagnosis; Clinical-tests; Air-sampling; Air-contaminants; Eye-disorders; Photography; Photographers
Contact
Vete Physio and Pharma Dept College of Veterinary Medicine University of Minnesota St Paul, Minn 55101
CODEN
JOCMA7
CAS No.
7761-88-8; 1301-96-8
Publication Date
19790601
Document Type
Journal Article
Funding Type
Grant
Fiscal Year
1979
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00219
Issue of Publication
6
ISSN
0096-1736
Source Name
Journal of Occupational Medicine
State
NY; MN
Performing Organization
University of Minnesota, Minneapolis, Minnesota
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