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Propanil-chloracne and methomyl toxicity in workers of a pesticide manufacturing plant.

Authors
Morse-DL; Baker-EL Jr.; Kimbrough-RD; Wisseman-CL
Source
Clin Toxicol 1979 Jul; 15(1):13-21
NIOSHTIC No.
00091913
Abstract
A questionnaire, medical records, and blood and urine samples were used to survey instances of occupationally related hospitalization among 102 workers at a pesticide facility in rural Arkansas that manufactured 1-lambda-methylthioethylideneamino methyl carbamate (16752775) (methomyl) and 3,4-dichloropropionanilide (709988) (propanil), a herbicide made from 3,4-dichloraniline (95761). Packaging workers had the highest rate of illness and hospitalization, and experienced blurred vision or pupillary constriction. Production workers exposed to dichloroaniline and propanil had the highest incidence of chloracne. Rabbit ear tests verified the chloracnegenic potential of propanil and 3,4- dichloroaniline. The authors conclude that a hazard exists in the manufacture and formulation of pesticides and herbicides, and report that industrial hygiene improvements in the packaging area have decreased the illness rate at the pesticide facility surveyed.
Keywords
NIOSH-Author; Data-collection; Medical-screening; Chemical-industry; Physiological-effects; Toxic-substances; Pest-control; Chemical-workers; Epidemiology; Biostatistics
CODEN
CTOXAO
CAS No.
16752-77-5; 709-98-8; 95-76-1
Publication Date
19790701
Document Type
Journal Article
Fiscal Year
1979
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
0009-9309
Source Name
Clinical Toxicology
State
AR; KS
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