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Toxic models of certain disorders of the nervous system - a teaching monograph.

Authors
Schaumburg-HH
Source
Neurotoxicology 1979 Jan; 1(1):209-220
NIOSHTIC No.
00091741
Abstract
Morphological models of human nervous system disease, developed through animal research, are described. Nervous system conditions are classified according to putative site of attack (neuron cell body, Schwann cell myelin, central peripheral distal axon, predominantly central axon, and proximal axon), and the associated human diseases are listed. Symptoms and chemical causes of neuronopathy, toxic myelinopathy, predominantly central axonopathy, and proximal axonopathy are reviewed. Central peripheral distal axonopathy, the most common peripheral nervous system reaction to exogenous toxins, is discussed and two animal model studies of this condition and human and animal correlations are considered. Industrial, environmental, and pharmaceutical agents associated with toxic axonopathies also are listed.
Keywords
NIOSH-Publication; Nervous-system-disorders; Laboratory-animals; Toxic-substances; Humans; Clinical-studies; Physiological-systems; Pathology; Neurotoxicity; Peripheral-nervous-system; Neurotoxic-effects
Contact
Pathology Albert Einstein Coll of Med 1300 Morris Park Avenue Bronx, N Y 10461
CODEN
NRTXDN
Publication Date
19790101
Document Type
Journal Article
Funding Amount
807725
Funding Type
Grant
Fiscal Year
1979
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00535
Issue of Publication
1
ISSN
0161-813X
Priority Area
Neurotoxic Disorders; Neurotoxic-effects
Source Name
Neurotoxicology
State
OH; NY
Performing Organization
Yeshiva University, New York, New York
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