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Organoisocyanates Occupational Hazards.

Authors
Anonymous
Source
NIOSH 1977 Oct:265-275
NIOSHTIC No.
00075432
Abstract
The molecular structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures, uses, and producer and user data are provided for organoisocyanates, toluene-2,4-diisocyanate (584849) (TDI), toluene-2,5-diisocyanate (91087), toluene-2,4-diisocyanate and 2,6-diisocyanate mixture, methyl-isocyanate (624839), phenyl-isocyanate (103719), m- chlorophenyl-isocyanate (2909388), and p-chlorophenyl-isocyanate (104121). The isocyanates in vapor form have a strongly irritating effect on all mucous membranes. After 8 days to two months of exposure to TDI, workers complain of eye, throat, and bronchial irritation, followed by asthmatic attacks. Case reports indicate that bronchospasm is the chief effect of TDI. A threshold limit value of 0.02ppm is recommended for TDI and methyl-isocyanate. (Contract No. 210-77-0120)
Keywords
NIOSH-Contract; Contract-210-77-0120; Herbicides; Toxic-substances; Cyanates; Irritants; Respiratory-system-disorders; Bronchial-asthma; Polyurethanes; Eye-irritants; Exposure-limits;
CAS No.
584-84-9; 91-08-7; 624-83-9; 103-71-9; 2909-38-8; 104-12-1;
Publication Date
19771001
Funding Type
Contract;
Fiscal Year
1978
NTIS Accession No.
NTIS Price
Identifying No.
Contract-210-77-0120
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Source Name
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
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