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Vibration Enhancement of Blood-Arterial Wall Macromolecule Transport.

Authors
Nerem-RM
Source
NIOSH 1977 Apr:37-43
Link
NIOSHTIC No.
00074689
Abstract
The influence of low-frequency, high-intensity, whole-body vibration on blood - arterial wall macromolecule transport has been investigated for iodine-131 labeled albumin (9006535). In-vivo studies of iodine-131-albumin uptake in the canine aorta during whole-body vibration have been carried out in anesthetized animals at a frequency of 10 hertz and with a peak to peak amplitude of 1.27 centimeters. These measurements, when compared with control measurements, indicate that during vibration there is a significant alteration in the pattern of albumin uptake in the aorta, together with an increased rate of uptake along its entire length. In-vitro studies have investigated the influence of sinusoidal pressure and flow variations on the transendothelial transport of albumin in serum perfused excised dog common carotid arteries. These results suggest that it is the vibration induced arterial wall shear stresses and a shear dependent transport process that are responsible for the enhancement of albumin uptake by the aortic wall during whole-body vibration.
Keywords
Biological-transport; Blood-chemicals; Proteins; Environment; Blood-vessels; Shear-stress; Physiological-effects;
CAS No.
9006-53-5;
Publication Date
19770401
Document Type
Conference/Symposia Proceedings;
Fiscal Year
1977
NTIS Accession No.
NTIS Price
Identifying No.
(NIOSH) 77-170
Source Name
Proceedings of the International Occupational Hand-Arm vibration Conference, NIOSH, (Paper presented at Cincinnati, Ohio, October 28-31, 1975), Cincinnati, Ohio, DHEW (NIOSH) Publication No. 77-170
State
OH;
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