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A cross-sectional epidemiologic survey of vinyl chloride workers.

Authors
Waxweiler-RJ; Falk-H; McMichael-A; Mallov-JS; Grivas-AS; Stringer-WT
Source
NIOSH 1977 Jun; :1-50
Link
NIOSHTIC No.
00072912
Abstract
The extent to which vinyl chloride monomer induces clinical detectable abnormalities among workers occupationally exposed was investigated during a cross-sectional medical survey at a chemical plant which had a polyvinylchloride polymerization operation, a polyvinyl chloride fabrication operation, and a rubber tire production operation. The survey of 433 predominantly white male employees, divided into four vinyl chloride exposure groups (never, light, heavy, former), determined the prevalence of illnesses and abnormalities based on data gathered by interview, medical examination, blood and pulmonary function tests, liver scans, and hand and chest X-rays. Age-adjusted analyses indicated that hepatomegaly, central nervous system symptoms, diastolic hypertension and spouses' fetal wastage (the latter two statistically significant) were more prevalent among past or present vinyl chloride exposed workers than among controls. Although vinyl chloride related respiratory system problems, acroosteolysis, Raynaud's phenomenon, and chromosome aberrations have been identified by other investigators, no excessive prevalence of these toxic effects was found in this population compared with industrial worker controls.
Keywords
NIOSH-Author; Vinyl-monomers; Chlorinated-ethylenes; Plastics-industry; Statistical-analysis; Chemical-processing-industry; Vinyl-plastics; Liver-disorders; PM9002862; Nervous-system-disorders; Circulatory-system-disorders; Reproduction-system-disorders; Epidemiology
CAS No.
75-01-4
Publication Date
19770601
Document Type
Numbered Publication
Fiscal Year
1977
NTIS Accession No.
PB-274193
NTIS Price
A04
Identifying No.
(NIOSH) 77-177
NIOSH Division
DSHEFS
Source Name
National Institute for Occupational Safety and Health
State
OH
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