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Binding of bismuth in the kidneys of the rate: The role of metallothionein-like proteins.

Authors
Szymanska-JA; Mogilnicka-EM; Kaszper-BW
Source
Biochem Pharmacol 1977 Feb; 26(3):257-258
NIOSHTIC No.
00071634
Abstract
Experiments were carried out in female rats injected subcutaneously with bismuth (7440699), in the form of radioactive labeled bismuth- chloride (7787602), in order to determine whether the level of metallothionein like proteins is elevated by repeated administration of the metal. According to the results obtained it follows that the elevated capacity of kidneys for bismuth, observed when the metal is administered repeatedly, is connected with metallothionein like proteins the level of which is enhanced by this element. Whether these proteins are identical with those which aid the storage of mercury in the kidneys requires further studies. (Grant No. PL-480-
Keywords
NIOSH-Publication; NIOSH-Grant; Protein-binding; Metal-poisoning; Heavy-metals; Biochemistry; Metalloproteins; Toxicology; Nephrotoxicity
CODEN
BCPCA6
CAS No.
7440-69-9; 7787-60-2
Publication Date
19770201
Document Type
Journal Article
Funding Type
Grant
Fiscal Year
1977
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-PL-480-05-009-2
Issue of Publication
3
ISSN
0006-2952
Source Name
Biochemical Pharmacology
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