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Prevalence, pathogenesis and control of byssinosis.

Authors
Kilburn-KH
Source
University of Missouri Medical Center, Columbia, Missouri 1976 Jan; :1-6
Link
NIOSHTIC No.
00071485
Abstract
The aims of the project are to test materials from cotton dust against cell systems in-vitro; to determine whether effects on lung in-vitro are predicted by leukocyte chemotaxis, ciliary inhibition and fibroblast proliferation; to determine chronic effects of materials which produce acute toxic effects; and to relate cellular pathology to airway narrowing in animals and man. During the grant period, lacinilene C-7-methyl-ether is identified as the green fluorescent material which is in aqueous and organic solvent extracts of cotton trash and carefully prepared isolated cotton bracts. The process of purification of the material is described. (Grant No. R01-OH-00511)
Keywords
NIOSH-Publication; Pulmonary-system-disorders; Respiratory-system-disorders; Pathogenesis; Dust-control; Cotton-industry; Chronic-diseases; Organic-dusts; Dust-inhalation
Contact
Medicine University of Missouri N424 Medical Center Columbia, MO 65201
Publication Date
19760101
Document Type
Final Grant Report
Funding Amount
230991
Funding Type
Grant
Fiscal Year
1976
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00511
NIOSH Division
OEP
Priority Area
Pulmonary-system-disorders; Respiratory-system-disorders
Source Name
University of Missouri Medical Center, Columbia, Missouri
State
MO
Performing Organization
University of Missouri Columbia, Columbia, Missouri
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