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A study of mechanisms of cadmium toxicity.

Authors
Anonymous
Source
NIOSH 1976 Jan; :1-31
Link
NIOSHTIC No.
00071471
Abstract
Results of studies of mechanisms of cadmium (7440439) toxicity over six years, including published and unpublished results, are summarized. Some details are given of studies on the effect of cadmium on microsomal activity, the effect of oral cadmium on zinc (7440666) and copper (7440508) metabolism, the dose response effects of long term administration of cadmium to male and female rats, the effect of cadmium on amino-levulinic-acid-dehydratase (9036377) activity, development of anode stripping voltammetry method for heavy metals, pathology of rats exposed to cadmium, and morphological changes induced by cadmium in relation to zinc nutrition. Cadmium toxicity is minimized by supraoptimal dietary intake of zinc and copper and increased by suboptimal levels. (Grant No. R01-OH-00337)
Keywords
NIOSH-Publication; Grants-other; Toxic-substances; Nutrients; Transition-metals; Analytical-methods; Sex-factors; Enzyme-activity; Morphology; Biochemical-reactions
Contact
Environmental Health Kettering Laboratory Eden & Bethesda Avenues Cincinnati, Ohio 45219
CAS No.
7440-43-9; 7440-66-6; 7440-50-8; 9036-37-7
Publication Date
19760101
Document Type
Final Grant Report
Funding Amount
311966
Funding Type
Grant
Fiscal Year
1976
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00337
NIOSH Division
OEP
Priority Area
Other Occupational Concerns; Grants-other
Source Name
Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, Terminal Report to NIOSH
State
OH
Performing Organization
University of Cincinnati, Cincinnati, Ohio
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