Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Chronic biological effects of methyl methacrylate vapor : I. Body and tissue weights, blood chemistries, and intestinal transit in the rat.

Authors
Tansy-MF; Kendall-FM; Benhayem-S; Hohenleitner-FJ; Landin-WE; Gold-M
Source
Environ Res 1976 Feb; 11(1):66-77
NIOSHTIC No.
00070678
Abstract
The effects upon body and tissue weights, various blood parameters, and intestinal transit time associated with chronic exposures of rats to monomeric methacrylate (80626) (MMA) vapor concentrations were investigated. The most remarkable and readily apparent phenomenon was the obvious lack of body fat in the group which had been exposed for 3 months to an MMA vapor concentration of 116ppm in air. It was determined that rats which have received a daily 8-hour exposure to 116ppm of MMA vapor for 6 months have significantly lower adiposity, as measured by the popliteal fat pad, than those of a similar group which have received sham exposures. It was also determined that protracted exposures to MMA vapor in this concentration were associated with a significant decrease in intestinal transit performance. Although cholesterol (57885), blood urea nitrogen, inorganic phosphate and serum glutamic-oxaloacetic- transaminase exhibited significant changes at 6 months post exposure, the differences were too small for interpretation.
Keywords
NIOSH-Publication; NIOSH-Grant; Grants-other; Gastrointestinal-system-disorders; Adipose-tissue; Biological-transport; Acrylics; Chronic-toxicity; Fat-metabolism; Blood-disorders; Toxicology; Hematology
Contact
Physiology and Biophysics Temple University 3223 N Broad Street Philadelphia, PA 19140
CODEN
ENVRAL
CAS No.
80-62-6; 57-88-5
Publication Date
19760201
Document Type
Journal Article
Funding Amount
78696.00
Funding Type
Grant
Fiscal Year
1976
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00518
Issue of Publication
1
ISSN
0013-9351
Priority Area
Other Occupational Concerns; Grants-other
Source Name
Environmental Research
State
PA
Performing Organization
Temple University, Philadelphia, Pennsylvania
TOP