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Sensory irritation by sulfite aerosols.

Authors
Alarie-Y; Wakisaka-I; Oka-S
Source
Environ Physiol Biochem 1973 Aug; 3(4):182-184
Link
NIOSHTIC No.
00056216
Abstract
Mice were exposed to aerosols of sodium-sulfite (7631905) and sodium- metabisulfite (7681574) and sensory irritation to the upper respiratory tract was measured. Sodium-sulfite was inactive, but sodium-metabisulfite was found to evoke sensory irritation in a fashion comparable to sulfur-dioxide. The findings indicate that sensory irritation is due to the presence of the bisulfite anion formed in the slightly alkaline pH of the nasal mucosa when animals are exposed to sodium-metabisulfite or sulfur-dioxide (7446095).
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Air-contaminants; Respiratory-irritants; Sensory-processes; Gases; Irritants;
Contact
Occupational Health University of Pittsburgh 130 DE Soto Street Pittsburgh, PA 15213
CODEN
ENPBBC
CAS No.
7631-90-5; 7681-57-4; 7446-09-5;
Publication Date
19730801
Document Type
Journal Article;
Funding Amount
332059.00
Funding Type
Grant;
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00367
Issue of Publication
4
ISSN
0300-5429
Priority Area
Pulmonary-system-disorders
Source Name
Environmental Physiology and Biochemistry
State
PA;
Performing Organization
University of Pittsburgh, Pittsburgh, Pennsylvania
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