Sensory irritation by sulfite aerosols.
Alarie-Y; Wakisaka-I; Oka-S
Environ Physiol Biochem 1973 Aug; 3(4):182-184
Mice were exposed to aerosols of sodium-sulfite (7631905) and sodium- metabisulfite (7681574) and sensory irritation to the upper respiratory tract was measured. Sodium-sulfite was inactive, but sodium-metabisulfite was found to evoke sensory irritation in a fashion comparable to sulfur-dioxide. The findings indicate that sensory irritation is due to the presence of the bisulfite anion formed in the slightly alkaline pH of the nasal mucosa when animals are exposed to sodium-metabisulfite or sulfur-dioxide (7446095).
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Air-contaminants; Respiratory-irritants; Sensory-processes; Gases; Irritants;
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Environmental Physiology and Biochemistry
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