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Some Physiological Aspects of Dysbarism-Induced Osteonecrosis.

Authors
Hills-BA
Source
NIOSH 1974:137-142
Link
NIOSHTIC No.
00053691
Abstract
The pathology of dysbarism-induced osteonecrosis appears to be related to a previous state of ischemia. The evidence for a hypothesis for delayed ischemia based on the hypersensitivity of the mineralization process to local water content. Different concentrations of gases can induce osmosis across sections of articular cartilage and other tissues. These effects are noted during compression and decompression, and when nitrous oxide is substituted for nitrogen. Removal of only 5-10% of water induces spontaneous nucleation of crystals. Rapid pressure changes in either compression or decompression should be avoided to prevent osteonecrosis.
Keywords
Bone-disorders; Physiology; Pressure-control; Safety-practices; Crystallization; Bone-structure; Workers;
CAS No.
10024-97-2; 7727-37-9;
Publication Date
19740101
Document Type
Conference/Symposia Proceedings;
Fiscal Year
1974
NTIS Accession No.
NTIS Price
Source Name
Dysbarism-Related Osteonecrosis, Proceedings, of a Symposium on Dysbaric Osteonecrosis, NIOSH, Cincinnati, Ohio
State
OH;
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