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Influence of relative humidity on functional effects of an inhaled SO2-aerosol mixture.

Authors
McJilton-CE; Frank-R; Charlson-RJ
Source
Am Rev Respir Dis 1976 Feb; 113(2):163-169
NIOSHTIC No.
00052075
Abstract
Lightly anesthetized guinea pigs are exposed to 1 part per million of sulfur dioxide and 1 milligram per cubic meter of sodium chloride aerosol, individually and in combination, at low and high relative humidities. Changes in pulmonary mechanical function characterized by an increase in flow resistance and decrease in compliance are seen only when the mixture is administered at high relative humidity. The effect is ascribed to absorption of the highly soluble sulfur dioxide into the droplet before inhalation.
Keywords
NIOSH-Publication; NIOSH-Grant; Toxic-gases; Inhalation; Respiratory-system-disorders; Particulates; Air-contaminants
Contact
Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
CODEN
ARDSBL
CAS No.
7446-09-5; 7647-14-5
Publication Date
19760201
Document Type
Journal Article
Funding Amount
420211
Funding Type
Grant
Fiscal Year
1976
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00340
Issue of Publication
2
ISSN
0003-0805
Priority Area
Pulmonary-system-disorders
Source Name
American Review of Respiratory Disease
State
WA
Performing Organization
University of Washington, Seattle, Washington
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