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Pilot study of closing volume in byssinosis.

Authors
Fairman-RP; Hankinson-J; Imbus-H; Lapp-NL; Morgan-WK
Source
Br J Ind Med 1975 Aug; 32(3):235-238
NIOSHTIC No.
00049398
Abstract
A study of the relative sensitivities of forced expiratory volume in one second, maximal mid-expiratory flow, and closing volume in the detection of subjects with byssinosis was carried out in a North Carolina cotton mill. Altogether 35 workers participated in the study. Of these, nine showed a decline in 10 percent or more during the first work shift that followed the weekend break. Twelve subjects showed a decrease in midexpiratory flow of 15 percent or more. In contrast only six workers exhibited a 10 percent increase in closing capacity, while ten showed a 10 percent increase in closing volume. Recent evidence of the magnitude of variability in closing volume maneuvers suggests that our chosen level of change was too low. A 40 percent change closing volume would have identified only five subjects. Closing volume is a more complex maneuver for the subject being tested and for the technician to perform, is more time consuming, and is subject to greater variation. To have any advantage over spirometry, closing volume would have to be appreciably more sensitive. The present findings study suggest that it is not. However, the midexpiratory flow may prove to be more sensitive than the forced expiratory volume in the detection of byssinosis.
Keywords
NIOSH-Author; Respiratory-function-tests; Respiratory-system-disorders; Diagnostic-tests; Cotton-industry; Textile-workers; Occupational-diseases; Test-methods
CODEN
BJIMAG
Publication Date
19750801
Document Type
Journal Article
Fiscal Year
1975
NTIS Accession No.
NTIS Price
Issue of Publication
3
ISSN
0007-1072
NIOSH Division
ALFORD
Priority Area
Respiratory-system-disorders
Source Name
British Journal of Industrial Medicine
State
NC; WV
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