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Effect of intrapulmonary water instillation on pulmonary lymph flow and composition.

Authors
Acevedo-JC; Robin-ED
Source
Am J Physiol 1972 Dec; 223(6):1433-1437
NIOSHTIC No.
00038652
Abstract
Intrapulmonary instillation of water in anesthetized, closed-chest, artificially ventilated dogs is followed by an increase in right lymphatic duct lymph flow. The increase is proportional to the amount of water instilled. A significant decrease in lymph sodium concentration without a significant change in lymph protein concentration is observed following the instillation of 10 milliliters per kilogram water. Evans blue concentration ratio is found to be 19, with a steady-state value of 10 at 5 hours. Intrapulmonary water instillation produces a striking decrease in lymph/plasma Evans blue ratio. In addition to water transport, lymphatics play a specific role in high molecular weight solute transport.
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Respiratory-system; Lymphatic-system; Lymph-plasma-ratio; Pulmonary-lymphatics
Contact
Physiology Stanford University Sch of Med Department of Medicine Palo Alto, Calif
CODEN
AJPHAP
Publication Date
19721201
Document Type
Journal Article
Funding Amount
668550.00
Funding Type
Grant
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00352
Issue of Publication
6
ISSN
1040-0605
Priority Area
Pulmonary-system-disorders; Respiratory-system
Source Name
American Journal of Physiology
State
CA
Performing Organization
Stanford University, Stanford, California
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