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Effect of depth of inhalation on aerosol persistence during breath holding.

Authors
Palmes-ED; Wang-C; Goldring-RM; Altshuler-B
Source
J Appl Physiol 1973 Mar; 34(3):356-360
NIOSHTIC No.
00038651
Abstract
Human subjects inhale aerosol bolus followed by 200-800 milliliters of clean air to a lung volume slightly below threshold limit concentration, to determine the effect of depth of inhalation on aerosol persistence in the respiratory tract during breath holding. The breath is then held from 0.5 to 20 seconds, after which a forced exhalation is made and aerosol recovery is measured as a function of inhaled volume and of time of breath. The bolus results are then compared with those for complete aerosol inhalations in which persistence is measured in the same way. Results show that depth of inhalation has a greater effect on persistence than would be predicted from some current lung models.
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Respiratory-system-disorders; Lung-disorders; Physiological-measurements
Contact
Environmental Medicine New York Univ Med Ctr 550 First Avenue New York, N Y 10016
CODEN
JAPHEV
Publication Date
19730301
Document Type
Journal Article
Funding Amount
80619.00
Funding Type
Grant
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00317
Issue of Publication
3
ISSN
8750-7587
Priority Area
Pulmonary-system-disorders; Respiratory-system-disorders
Source Name
Journal of Applied Physiology
State
NY
Performing Organization
New York University, New York, New York
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