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"Nonspecific" interstitial pulmonary fibrosis: association with asbestos fibers detected by electron microscopy.

Authors
Miller-A; Langer-AM; Teirstein-AS; Selikoff-IJ
Source
N Engl J Med 1975 Jan; 292(2):91-93
NIOSHTIC No.
00038208
Abstract
The case history is described of a 63 year old clerk with ventilatory alterations and evidence of diffuse honeycombing, in whom electron microscopy of a lung biopsy specimen demonstrated the presence of a large number of very small chrysotile (12001295) asbestos fibers. The case reported documents the association of submicroscopical chrysotile fibrils with severe pulmonary fibrosis, in the absence of fibers demonstrable by light microscopy. The asbestos content of the patient's lung was calculated to be a minimum 0.45 grams, an amount consistent with a low level occupational exposure.
Keywords
Pulmonary-system-disorders; Lung-fibrosis; Respiratory-system-disorders; Asbestos-dust; Fibrogenic-dusts; Particle-size-distribution; Respiratory-functions; Histopathology; Asbestosis; Radiology
Contact
Community Medicine Mount Sinai School of Medicine Fifth Avenue and 100 Street New York, N Y 10029
CODEN
NEJMAG
CAS No.
12001-29-5
Publication Date
19750109
Document Type
Journal Article
Funding Amount
629948
Funding Type
Grant
Fiscal Year
1975
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00320
ISSN
0028-4793
Priority Area
Pulmonary-system-disorders; Respiratory-system-disorders
Source Name
New England Journal of Medicine
State
NY
Performing Organization
Mount Sinai School of Medicine, New York, New York
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