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Repeated topical applications of 1,2,4-trichlorobenzene: effects on rabbit ears.

Authors
Powers-MB; Coate-WB; Lewis-TR
Source
Arch Environ Health 1975 Apr; 30(4):165-167
NIOSHTIC No.
00037270
Abstract
Increasing concentrations of 1,2,4-trichlorobenzene (120821) were applied topically to the ventral surface of rabbit ears three times weekly for 13 weeks. Skin response to 1,2,4-trichlorobenzene was characterized grossly by dermal irritation directly related to the concentration of test material; there were the associated histologic changes of acanthosis and hyperkeratosis, but no primary folicular involvement characteristic of acneform dermatitis.
Keywords
NIOSH-Contract; NIOSH-Author; NIOSH-Publication; Contract-099-73-0083; Skin-disorders; Aromatic-hydrocarbons; Benzenes; Chlorinated-hydrocarbons
CODEN
AEHLAU
CAS No.
120-82-1
Publication Date
19750401
Document Type
Journal Article
Funding Type
Contract
Fiscal Year
1975
NTIS Accession No.
NTIS Price
Identifying No.
Contract-099-73-0083
Issue of Publication
4
ISSN
0003-9896
Source Name
Archives of Environmental Health
State
VA; OH
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