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Measurement of pulmonary air spaces using aerosols.

Authors
Palmes-ED
Source
Arch Intern Med 1973 Jan; 131(1):76-79
NIOSHTIC No.
00037140
Abstract
During investigation of the relationship of aerosol persistence in the human respiratory tract to the dimensions of the air spaces, procedures were developed in which the subject inhaled a fixed volume of aerosol and held his breath at known lung volumes for a series of times prior to exhalation. With appropriate correcting, the persistence of aerosol could be measured as a function of time of breath holding. The distance that particles must be moved during breath holding by sedimentation or diffusion to reach a wall of the respiratory tract is determined by the size of the air spaces; the time required to reach the wall also depends on this distance. The persistence of aerosol, therefore, provides an index of the size of the air spaces containing aerosol during breath holding.
Keywords
NIOSH-Publication; NIOSH-Grant; Lung-disorders; Respiratory-system-disorders; Inhalants; Physiological-measurements; Air-space-measurement
Contact
Environmental Medicine New York Univ Med Ctr 550 First Avenue New York, N Y 10016
CODEN
AIMDAP
Publication Date
19730101
Document Type
Journal Article
Funding Amount
80619.00
Funding Type
Grant
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00317
Issue of Publication
1
ISSN
0003-9926
Source Name
Archives of Internal Medicine
State
NY
Performing Organization
New York University, New York, New York
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