Prevention of occupational skin diseases from exposure to chromic acid and chromates: use of ascorbic acid.
Cutis 1974 Apr; 13:569-574
A review of preventive measures for the control of the irritant and sensitizing action caused by chromates reveals that ascorbic acid is effective in preventing and treating a variety of such adverse reactions. A 10 percent ascorbic-acid (50817) solution shortens the time required for the healing of skin ulcers produced by potassium- chromate (7789006) in guinea-pigs, while the impregnation of ascorbic-acid into the filters of respirators enhances protection against inhalation of chromic-acid (7738945) mist. A preventive regimen with 10 percent aqueous ascorbic-acid proved effective in the printing industry and in the lithographing industry.
NIOSH-Publication; NIOSH-Grant; Skin-disorders; Preventive-medicine; Metal-poisoning; Chromium-poisoning; Hypersensitivity; Skin-irritation; Heavy-metals; Vitamins; Skin-protection; Personal-protective-equipment; Respiratory-protection;
Medicine, Dermatology Univ of Pennsylvania Hospital Duhring Laboratory Building Philadelphia, PA 19104
50-81-7; 7789-00-6; 7738-94-5;
University of Pennsylvania, Philadelphia, Pennsylvania