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Factors affecting the excretion of industrial poisons.

Authors
Elkins-HB; Pagnotto-LD
Source
Massachusetts Department of Labor and Industries, Division of Occupational Hygiene, Boston, Massachusetts, 1974 Jan; :1-4
Link
NIOSHTIC No.
00036309
Abstract
A study of the effects of methylene-chloride (75092) exposure on carboxyhemoglobin of workers in a plastic film plant indicates that nonsmoking workers at the end of the work shift with carboxyhemoglobin of 10 percent have exposures to methylene chloride in excess of a CGIH TLV of 250 ppm for that solvent. Three methods of expressing urine concentration of toxic compounds and their metabolites are discussed. A study of benzene (71432) exposure in the rubber coating industry is reviewed. A good correlation is found between exposure and urinary mercury (7439976) excretion in a study of the hazards of vacuum cleaning the rugs in a dental office. Mercury elimination takes a long time to complete even after the stoppage of exposure. Surveillance of workers exposed to chloroform (67663) shows the need for regular blood tests and urine tests. Methyl-ethyl-ketone (78933) is not metabolized to any great extent, but rapidly excreted in the urine, returning to normal levels overnight.
Keywords
NIOSH-Grant; Toxic-substances; Blood-analysis; Rubber-industry; Urinalysis; Mercury-poisoning; Blood-disorders
Contact
Labor and Industries 39 Boylston Street Boston, Mass 02116
CAS No.
75-09-2; 71-43-2; 7439-97-6; 67-66-3; 78-93-3
Publication Date
19740101
Document Type
Final Grant Report
Funding Amount
70865
Funding Type
Grant
Fiscal Year
1974
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00309
NIOSH Division
OEP
Source Name
Massachusetts Department of Labor and Industries, Division of Occupational Hygiene, Boston, Massachusetts, 4 pages, 5 references
State
MA
Performing Organization
Massachusetts Dept of Labor & Industries, Boston, Massachusetts
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