Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Alterations in hepatocytes after manipulation of the diet: copper, zinc and cadmium interactions.

Authors
Miller-ML; Murthy-L; Basom-CR; Petering-HG
Source
Am J Anat 1974 Sep; 141(1):23-39
NIOSHTIC No.
00036271
Abstract
Morphometric analyses of liver parenchymal cells are performed on ale albino rats fed a semipurified diet supplemented with two levels of copper (7440508) and zinc (7440666). The metals are administered in demineralized drinking water to four groups of animals at two levels. Cadmium (7440439) is also administered in the drinking water daily to one group of rats. Hepatocytes from rats fed the semipurified diet with low copper and zinc plus cadmium show a significant increase in smooth endoplasmic reticulum compared to animals fed the semipurified diet alone. Smooth endoplasmic reticulum increases when diets include chow and cadmium whereas rough endoplasmic reticulum decreases.
Keywords
NIOSH-Publication; NIOSH-Grant; Liver-disorders; Metal-poisoning; Water-contamination; Morphology; Cytopathology; Food-contamination
Contact
Environmental Health Kettering Laboratory Eden & Bethesda Avenues Cincinnati, Ohio 45219
CODEN
AJANA2
CAS No.
7440-50-8; 7440-66-6; 7440-43-9
Publication Date
19740901
Document Type
Journal Article
Funding Amount
311966
Funding Type
Grant
Fiscal Year
1974
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00337
Issue of Publication
1
ISSN
0002-9106
Source Name
American Journal of Anatomy
State
OH
Performing Organization
University of Cincinnati, Cincinnati, Ohio
TOP