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Two patterns for bronchial damage from inhaled materials.

Authors
Kilburn-KH; Hudson-AR; Halprin-GM; McKenzie-WN; Merchant-JA
Source
Chest 1974 Apr; 65(4):61-62
NIOSHTIC No.
00028116
Abstract
Morphology of distal airway cells, and the leukocyte recruitment phenomenon are studied after exposure of hamsters or guinea-pigs to dust or aerosol. Bronchial damage from inhaled materials may consist of epithelial cell vacuolization, nuclear extrusion and cellular extrusion, or polymorphonuclear leukocyte recruitment. Nonparticulate materials given as aerosols, particularly gossypol and paraquat (1910425), are deposited out to peripheral airways as judged by cell damage, while particles recruit leukocytes without producing ultrastructural damage to cells.
Keywords
NIOSH-Publication; NIOSH-Grant; Respiratory-system-disorders; Airborne-particulates; Air-contamination; Herbicides; Byssinosis; Cytopathology
Contact
Medicine Duke University ED Ctr Durham, N C 27706
CODEN
CHETBF
CAS No.
1910-42-5
Publication Date
19740401
Document Type
Journal Article
Funding Amount
265637.00
Funding Type
Grant
Fiscal Year
1974
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00302
Issue of Publication
4
ISSN
0012-3692
Priority Area
Respiratory-system-disorders
Source Name
Chest
State
NC
Performing Organization
Duke University, Durham, North Carolina
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