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Acute effects of ozone on cat lungs II. Structural.

Authors
Boatman-ES; Sato-S; Frank-R
Source
Am Rev Respir Dis 1974 Aug; 110(2):157-169
NIOSHTIC No.
00026380
Abstract
Cats exposed to various concentrations of ozone (10028156) for several hours showed dose related cytological changes in the airways and lung parenchyma. The most consistent ultrastructural changes were cytoplasmic vacuolization of ciliated cells and condensed mitochondria with abnormal cristae configuration. Also described are alveolar ultrastructural changes. Increased airway resistance was dose related but the decline of diffusing capacity was not affected by the concentration of ozone.
Keywords
NIOSH-Publication; NIOSH-Grant; Toxicity; Respiratory-disorders; Cytopathogenicity; Electron-microscopy; Respiratory-functions; Lung-disorders; Respiratory-irritants; Oxidizers; Cytotoxicity
CODEN
ARDSBL
CAS No.
10028-15-6
Publication Date
19740801
Document Type
Journal Article
Funding Amount
420211.00
Funding Type
Grant;
Fiscal Year
1974
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00340
Issue of Publication
2
ISSN
0003-0805
Source Name
American Review of Respiratory Disease
State
WA
Performing Organization
Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
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