Seven hundred ninety two active granite shed workers from Barre, Vermont, were studied to estimate the effect of granite dust on pulmonary function. From a complete occupational history and a comprehensive evaluation of the past and present environment, a total lifetime dust and quartz (1317799) exposure is established for each worker. Granite dust and quartz cause a decrease in forced vital capacity (FVC), forced expiratory volume in one second (FEV1.0), and total lung capacity (TLC), but not in residual volume (RV). This decrease is estimated by multiple regression analysis at 2 milliliters per dust year. A dose response for quartz and granite dust shows that the midpoint, 50 percent, is 32.5 dust years for total dust and 35 quartz years for free silica (7631869). From the present data, standards for exposure to both granite dust and quartz can be derived.