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Arterial blood gas tensions and lung function during acute responses to hemp dust.

Authors
Merino-VL; Lombart-RL; Marco-RF; Carnicero-AB; Guillen-FG; Bouhuys-A
Source
Am Rev Respir Dis 1973 May; 107(5):809-815
NIOSHTIC No.
00023035
Abstract
Exposure to hemp fiber dust for 15 minutes to 3 hours of 3 volunteers (former hemp workers) results in symptoms of byssinosis, and reductions in one-second forced expiratory volume and arterial oxygen tension. The decrease in arterial oxygen tension occurs in men with normal and abnormal one-second expiratory volumes before dust exposure. The decreases of one-second forced expiratory volume and of arterial oxygen (7782447) tension correlate significantly while changes of arterial carbon-dioxide (124389) tension are generally small. Results indicate that hemp exposure causes changes in both gas exchange and lung mechanics. Increased nonuniformity of gas distribution and its effect on ventilation-perfusion relations account for the altered gas exchange. The evidence points to the need for stringent control of dust exposure in textile workers at risk of byssinosis.
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Pulmonary-function-tests; Pulmonary-function; Textile-fibers; Blood-gas-analysis; Respiratory-gas-analysis; Dust-inhalation; Organic-dusts; Textiles-industry; Airway-obstruction
Contact
John B Pierce Fdn Lab John B Pierce Fdn Lab 290 Congress Avenue New Haven, Conn 06519
CODEN
ARDSBL
CAS No.
7782-44-7; 124-38-9
Publication Date
19730501
Document Type
Journal Article
Funding Amount
513539
Funding Type
Grant
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00304
Issue of Publication
5
ISSN
0003-0805
Priority Area
Pulmonary-system-disorders
Source Name
American Review of Respiratory Disease
State
CT
Performing Organization
John B Pierce Fdn of Conn Inc, New Haven, Connecticut
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