Production of tolerance to ozone: an immunochemical phenomenon?
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Consumer Protection and Environmental Health Service, Environmental Control Administration, Bureau of Occupational Safety and Health, RR-13, 1969 Apr; :1-8
The immunochemical basis for development of tolerance to ozone through a single nonlethal exposure is studied in animals by observation of serum glycoproteins increase during the course of immunity development, and use of the agar double-diffusion technique for indicating identity or non-identity of precipitating antigen- antibody reactions. No significant increases in tolerance or of serum glycoproteins are observed, nor are additional precipitin lines formed, with results not supporting the immunochemical theory.
Toxic-gases; Irritants; Immunology; Analytical-techniques; Serology; Blood-chemical-reactions; Adaptability
Bureau of Occupational Safety and Health