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Talc: a possible occupational and environmental carcinogen.

Authors
Blejer-HP; Arlon-R
Source
J Occup Med 1973 Feb; 15(2):92-97
NIOSHTIC No.
00018396
Abstract
Talcs can be contaminated with asbestos minerals. Both talc and asbestos produce various fibrosing conditions. Asbestos as well as asbestos contaminated talc are known to be occupationally associated with excess mortality from various cancers. Ingestion, inhalation, skin, vaginal and other routes of talc exposure and absorption might, therefore, be associated with increased environmental and consumer health risks. Environmentally produced deposition and retention of talc particles in human lungs appear to be widespread. Talc particles have been found in some normal ovaries, as in the core of primary cancers of the ovary, endometrium, and cervix of nonoccupationally talc or asbestos exposed women in Britain. Many talc dusting powders and California processed talc coated rices tested were found to contain significant amounts of asbestos. Experimental animal exposure studies are needed to ascertain any possible carcinogenicity of pure talc which cannot presently be said to be more than adventitious.
Keywords
NIOSH-Author; Asbestos; Carcinogens; Fibrosis; Magnesium-compounds; Occupational-diseases
CODEN
JOCMA7
Publication Date
19730201
Document Type
Journal Article
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
0096-1736
Source Name
Journal of Occupational Medicine
State
CA
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