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Surface spreading of lung alveolar surfactant.

Authors
Mendenhall-RM
Source
Respir Physiol 1972 Oct; 16(2):175-178
NIOSHTIC No.
00018390
Abstract
Indications of the rate of spreading of lung alveolar surfactant (LAS) in the presence of known differentials of surface tension were sought. LAS was found to spread and abolish surface tension differences at a rate measured in centimeters/second whether the initial surface tension differential was relatively high (35 dynes/cm) or low (15 dynes/cm). The laws of capillarity would require surface tension in alveoli to be directly proportional to their size; however, groups of alveoli of varying sizes are contiguous and, forming a single surface, possibly act as a unit with respect to surface tension because of rapid equalization of differences in surface tension. LAS originates its movement in the alveoli and therefore serves as an agent to remove particulate matter from lung alveoli.
Keywords
Alveolar-cell; Interfacial-tension; Lungs; NIOSH-Author; Surface-active-agent; Author Keywords: Alveolar surfactant; Lung stability; Removal of particulates; Surface tension; Tracheal surfactant
Contact
Richard M. Mendenhall, Department of Health, Education, and Welfare, Public Health Service, National Institute for Occupational Safety and Health, 1014 Broadway, Cincinnati, Ohio 45202, U.S.A.
CODEN
RSPYAK
Publication Date
19721001
Document Type
Journal Article
Fiscal Year
1973
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
0034-5687
Source Name
Respiration Physiology
State
OH
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