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Criteria for a recommended standard... occupational exposure to toluene diisocyanate.

Authors
Anonymous
Source
NIOSH 1973 Jan; :1-106
NIOSHTIC No.
00011549
Abstract
Presentation of the criteria and the recommended standard based thereon which were prepared to meet the need for preventing occupational diseases arising from exposure to toluene-diisocyanate (1321386) (TDI). The proposed standard applies only to the processing, manufacture, and use of TDI products as applicable under the Occupational Safety and Health Act of 1970. TDI is an irritating material, both in its liquid and airborne forms, producing skin and respiratory tract irritation, and causing sensitization. Sensitized workers are subject to asthmatic attacks on re-exposure to extremely low concentrations of TDI in air. Environmental limits are recommended to prevent acute and chronic irritation and sensitization of workers but not prevent a response in already sensitized workers, because available knowledge does not indicate any safe concentration for such persons. There are conflicts in available epidemiological data. In addition, methods for sampling and analysis of airborne TDI are inadequately sensitive. Thus, further research in these areas is needed in order to demonstrate means by which these recommended standards can be refined.
Keywords
NIOSH-Contract; Contract-099-72-0128; Legislation; Toxicology; Safety-procedure; Work-practices; Hazardous-substances; Tolerances; Air-contamination; Sensitivity; Syndrome; Risks; Biological-effects; Measurement; Respiratory-irritants; Dermatosis; Isocyanates
CAS No.
1321-38-6
Publication Date
19730101
Document Type
Numbered Publication; Criteria Document
Funding Type
Contract
Fiscal Year
1973
NTIS Accession No.
PB-222220
NTIS Price
A07
Identifying No.
(NIOSH) 73-11022; Contract-099-72-0128
Source Name
National Institute for Occupational Safety and Health
State
MD
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