What will the program achieve?
Research Goal 4.5 - Prevent hearing loss by understanding the role of genetics in susceptibility to noise
Understanding genetic susceptibility to noise-induced hearing loss will continue to be an important effort for the HLR program. The program is continuing to partner with researchers at the University of Cincinnati and the Case-Reserve School of Medicine attempting to identify genes which are affected by noise exposure. These genes are related to recovery and repair of the ear after noise. Current research focuses on understanding the transition zone between exposures producing temporary threshold shift (recoverable) and permanent threshold shift (non-recoverable). With the completion of the sequencing of the mouse genome, many-high powered techniques and strategies are expected to be available to attack this problem.