What will the program achieve?
Research Goal 4.4 - Improve detection and prevention of occupational hearing loss by understanding the aging component
Presbycusis, the loss of hearing that gradually occurs in most individuals as they grow older, is a difficult phenomenon to study because it requires a long-term commitment of resources. The HLR program is involved with the Fels Longitudinal Study by providing audiometric resources and training to staff. Data should start becoming available for these subjects in the next 2-3 years.
At the 2002 consensus meeting in Nottingham, England, a consensus report was not able to be generated; but recently the group was re-contacted by e-mail in an effort to develop a document outlining the controversies in the role of aging in noise-induced hearing loss.
The HLR program made available to international researchers, the NIOSH-sponsored database of hearing conservation records. This database was the basis of the Franks & Davis report (2002).
An additional mouse study, using the B6 strain known to develop presbycusis early in life, is planned with the University of Cincinnati to further investigate pharmacological interventions in presbycusis. Other inhibitors of ROS are planned to be tested over the next few years.