International Chemical Safety Cards

2-BUTYNE-1,4-DIOL ICSC: 1733
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
1,4-Butynediol
1,4-Dihydroxy-2-butyne
But-2-yne-1,4-diol
2-Butynediol
C4H6O2/OHCH2CCCH2OH
Molecular mass: 86.1
6 Harmful - Stow Away from Foodstuffs placard 6 Poison placard ICSC #    1733
CAS #     110-65-6
RTECS # ES0525000
UN #        2716
EC #         603-076-00-9
November 13, 2008 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible.
NO open flames.
Water spray, alcohol-resistant foam, dry powder, carbon dioxide.
EXPLOSION Risk of explosion on contact with base(s) , oxidants , halogens.


EXPOSURE
STRICT HYGIENE!

 •INHALATION Cough. Sore throat. Burning sensation. Shortness of breath. Laboured breathing.
Ventilation (not if powder).
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
 •SKIN Redness. Pain. Skin burns.
Protective clothing. Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention.
 •EYES Redness. Pain. Burns .
Face shield or eye protection in combination with breathing protection if powder.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
 •INGESTION Burns in mouth and throat. Burning sensation in the throat and chest. Abdominal pain.
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: Chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.
Separated from incompatible materials. See Chemical Dangers. Cool. Store in an area without drain or sewer access. mperature should be kept below 40C and storage times longer than a few month should be avoided because the butynediol flakes tend to set up.
Do not transport with food and feedstuffs.
C symbol
T symbol
R: 21-23/25-34-43-48/22
S: 1/2-25-26-36/37/39-45-46
UN Hazard Class: 6.1
UN Packing Group: III
Signal: Danger
Corr-Skull-Health haz
Toxic if swallowed
Harmful in contact with skin
Toxic if inhaled mist
Causes severe skin burns and eye damage
May cause allergic skin reaction
May cause damage to liver, kidney and blood through prolonged or repeated exposure
Harmful to aquatic life
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1733 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

2-BUTYNE-1,4-DIOL ICSC: 1733
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PHYSICAL STATE; APPEARANCE:
YELLOW SOLID IN VARIOUS FORMS

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating producing toxic and corrosive fumes.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: (Inhalable fraction) 0.2 mg/m Skin absorption (H). Sensitization of skin (Sh).
Peak limitation category: I(1). Pregnancy risk group: C.
(DFG 2008).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion . Serious local effects by all routes of exposure.

INHALATION RISK:
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20C ; on spraying or dispersing, however, much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
Corrosive. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood, resulting in anaemia, and kidneys and liver, resulting in
PHYSICAL
PROPERTIES
Decomposes at >160 C
Melting point: 58C
Relative density (water = 1): 1.1
Solubility in water, g/100 ml at 20C: 75
(good)
Vapour pressure, Pa at 20C: 0.2
Relative vapour density (air = 1): 3.0
Flash point: 152C
Auto-ignition temperature: 335C
Octanol/water partition coefficient as log Pow: -0.73
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is harmful to aquatic organisms.
N O T E S
There is no odour warning even when toxic concentrations are present. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Transport Emergency Card: TEC (R)-61GT2-III
ADDITIONAL INFORMATION


ICSC: 1733 2-BUTYNE-1,4-DIOL
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.