International Chemical Safety Cards

NICOTINAMIDE ICSC: 1703
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Pyridine-3-carboxylamide
3-Pyridinecarboxamide
Niacinamide
C6H6N2O
Molecular mass: 122.1
ICSC #    1703
CAS #     98-92-0
RTECS # QS3675000
April 08, 2008 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Water spray, foam, powder, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

 •INHALATION Cough.
Avoid inhalation of dust.
Fresh air, rest.
 •SKIN
Protective gloves.
Rinse skin with plenty of water or shower.
 •EYES Redness. Pain.
Safety goggles
Rinse with plenty of water (remove contact lenses if easily possible).
 •INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth. Give one or two glasses of water to drink.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: particulate filter adapted to the airborne concentration of the substance. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.
Separated from oxidants.

Signal: Warning
Causes eye irritation
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1703 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

NICOTINAMIDE ICSC: 1703
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PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALLINE POWDER.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
On combustion, forms toxic gases, including nitrogen oxides. Reacts with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.


ROUTES OF EXPOSURE:


INHALATION RISK:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
PHYSICAL
PROPERTIES
Sublimation
Melting point: 127-131C
Density: 1.4
g/cm
Solubility in water, g/100 ml at 20C: 100
(very good)
Vapour pressure, kPa at 35C: 3.1
Relative vapour density (air = 1): 4.2
Flash point: 182C
Auto-ignition temperature: 480C
Octanol/water partition coefficient as log Pow: -0.38
ENVIRONMENTAL
DATA

N O T E S
ADDITIONAL INFORMATION


ICSC: 1703 NICOTINAMIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.