International Chemical Safety Cards N,N'-DIACETYLBENZIDINE ICSC: 1678 4,4'-Diacetamidobiphenyl N,N'-(1,1'-Biphenyl)-4,4'-diylbisacetamide 4',4'''-Biacetanilide 4,4'-Diacetylbenzidine DABZ C16H16N2O2 / (C6H4NHCOCH3)2 Molecular mass: 268.3 ICSC #    1678 CAS #     613-35-4 RTECS # DT2800000 EC #         612-044-00-3 April 20, 2007 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE In case of fire in the surroundings: use appropriate extinguishing media. EXPLOSION EXPOSURE AVOID ALL CONTACT!  •INHALATION Cough. Closed system and ventilation. Fresh air, rest.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Safety spectacles Rinse with plenty of water (remove contact lenses if easily possible).  •INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: particulate filter adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. mutagenicity, carcinogenicity and structural analogy with benzidine (N; R50/53 : Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. ) Separated from strong oxidants and food and feedstuffs . Well closed. Store in an area without drain or sewer access. Xn symbol R: 20/21/22 S: 2-22-36 Signal: Warning Health haz Suspected of causing genetic defects Suspected of causing cancer May cause damage to blood and kidneys through prolonged or repeated exposure SEE IMPORTANT INFORMATION ON BACK ICSC: 1678 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards N,N'-DIACETYLBENZIDINE ICSC: 1678 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: WHITE CRYSTALS . PHYSICAL DANGERS: CHEMICAL DANGERS: On contact with hot surfaces or flames this substance decomposes forming nitrogen oxides. Reacts with strong oxidants . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body in hazardous amounts by inhalation of its aerosol and by ingestion. INHALATION RISK: A harmful concentration of airborne particles can be reached quickly when dispersed EFFECTS OF SHORT-TERM EXPOSURE: May cause mechanical irritation to the eyes and the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood and kidneys , resulting in the formation of methaemoglobin, anaemia and kidney impairment. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Melting point: 327-330°C Solubility in water: none Octanol/water partition coefficient as log Pow: 1.97 ENVIRONMENTAL DATA N O T E S Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Environmental effects from the substance have not been investigated. ADDITIONAL INFORMATION ICSC: 1678 N,N'-DIACETYLBENZIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.