International Chemical Safety Cards 3,3'-DIAMINOBENZIDINE ICSC: 1666 3,3',4,4'-Biphenyltetramine (1,1'-Biphenyl)-3,3',4,4'-tetraamine 3,3',4,4'-Diphenyltetramine 3,3',4,4'-Tetraaminobiphenyl Biphenyl-3,3',4,4'-tetrayltetraamine C12H14N4 / (NH2)2C6H3C6H3(NH2)2 Molecular mass: 214.3 ICSC #    1666 CAS #     91-95-2 RTECS # DV8750000 April 20, 2007 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION EXPOSURE AVOID ALL CONTACT!  •INHALATION Closed system and ventilation. Fresh air, rest.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Safety spectacles Rinse with plenty of water (remove contact lenses if easily possible).  •INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give one or two glasses of water to drink. Seek medical attention if you feel unwell SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: particulate filter adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Dry. Well closed. Separated from food and feedstuffs and strong oxidants. Store in an area without drain or sewer access. Signal: Warning Excl mark-Health haz Harmful if swallowed Suspected of causing genetic defects Suspected of causing cancer SEE IMPORTANT INFORMATION ON BACK ICSC: 1666 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 3,3'-DIAMINOBENZIDINE ICSC: 1666 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: 0\RED TO BROWN HYGROSCOPIC SOLID IN VARIOUS FORMS PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing nitrogen oxides Reacts with strong oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK: Carcinogen category: 3B (DFG 2006). ROUTES OF EXPOSURE: The substance can be absorbed into the body in hazardous amounts by inhalation of its aerosol and by ingestion. INHALATION RISK: A harmful concentration of airborne particles can be reached quickly. EFFECTS OF SHORT-TERM EXPOSURE: May cause mechanical irritation to the eyes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Melting point: 176°C (very poor) Solubility in water: Flash point: >200°C Auto-ignition temperature: 560°C Octanol/water partition coefficient as log Pow: 0.09 ENVIRONMENTAL DATA N O T E S Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Environmental effects from the substance have not been investigated. The recommendations on this Card also apply to 3,3'-Diaminobenzidine tetrahydrochloride, CAS-number 7411-49-6. ADDITIONAL INFORMATION ICSC: 1666 3,3'-DIAMINOBENZIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.