International Chemical Safety Cards

1-BROMO-3-CHLOROPROPANE ICSC: 1665
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
1-Chloro-3-bromopropane
Trimethylene chlorobromide
C3H6BrCl / Cl(CH2)3Br
Molecular mass: 157.4
6 Harmful - Stow Away from Foodstuffs placard 6 Poison placard ICSC #    1665
CAS #     109-70-6
RTECS # TX4113000
UN #        2688
April 18, 2007 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder , water spray , foam , carbon dioxide .
EXPLOSION Above 57C explosive vapour/air mixtures may be formed.
Above 57C use a closed system, ventilation, and explosion-proof electrical equipment.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE


 •INHALATION Tremor. Drowsiness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
 •SKIN
Protective gloves.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
 •EYES
Safety spectacles .
Rinse with plenty of water (remove contact lenses if easily possible).
 •INGESTION (see Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place.
Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access.
Do not transport with food and feedstuffs.
UN Hazard Class: 6.1
UN Packing Group: III
Signal: Danger
Flame-Skull-Health haz
Flammable liquid and vapour
Harmful if swallowed
May be harmful in contact with skin
Toxic if inhaled
May cause damage to central nervous system and liver
Harmful to aquatic life
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1665 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

1-BROMO-3-CHLOROPROPANE ICSC: 1665
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PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID .

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on burning producing toxic and corrosive gases including hydrogen bromide (See ICSC 0282). and hydrogen chloride (See ICSC 0163).

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the central nervous system and liver , resulting in impaired functions . o human data. But structural analogy gives suspicion to CNS effects, corroborated by animal oral application of 900 mg/kg: exicitation, followed by sleepiness and muscular weaknes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
PHYSICAL
PROPERTIES
Boiling point: 143.3C
Melting point: -58.9C
Relative density (water = 1): 1.6
Solubility in water, g/100 ml at 25C: 0.224
Vapour pressure, kPa at 25C: 0.85
Relative vapour density (air = 1): 5.4
Relative density of the vapour/air-mixture at 20C (air = 1): 1.03
Flash point: 57C
Explosive limits, vol% in air: 3.2 - 8.6
Octanol/water partition coefficient as log Pow: 2.18
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is harmful to aquatic organisms.
N O T E S
Transport Emergency Card: TEC (R)-61S2688 or TEC (R)-61GT1-III
ADDITIONAL INFORMATION


ICSC: 1665 1-BROMO-3-CHLOROPROPANE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.