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ISOBUTYL NITRITE

ICSC: 1651

Nitrous acid, 2-methylpropyl ester
Nitrous acid, isobutyl ester
C4H9NO2 / (CH3)2CHCH2NO2
Molecular mass: 103.1
ICSC #    1651
CAS #     542-56-3
RTECS # RA0805000
UN #        1992
EC #         007-017-00-2
April 05, 2006 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Dry powder. Carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
AVOID ALL CONTACT!

 •INHALATION Sore throat. Headache. Dizziness. Blue lips or finger nails. Blue skin. Nausea. Confusion. Convulsions. Unconsciousness. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
 •SKIN
Protective gloves. Protective clothing.
Rinse and then wash skin with water and soap.
 •EYES
Safety spectacles.
Rinse with plenty of water (remove contact lenses if easily possible).
 •INGESTION (See Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: self-contained breathing apparatus. Evacuate danger area! Consult an expert! Ventilation. Remove all ignition sources. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer.
Fireproof. Separated from acids. Well closed.
Do not transport with food and feedstuffs.
Note: E
F symbol
T symbol
R: 11-20/22-45-68
S: 53-45
UN Hazard Class: 3
UN Subsidiary Risks: 6.1
UN Packing Group: III
Signal: Danger
Flame-Skull-Health haz
Highly flammable liquid and vapour
Harmful if swallowed
Toxic if inhaled vapour
Suspected of causing cancer
Causes damage to blood
ICSC: 1651 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ISOBUTYL NITRITE

ICSC: 1651

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PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance decomposes on burning producing toxic gases including nitrogen oxides.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: (Ceiling value) 1 ppm, A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued (ACGIH 2006).
MAK not established.


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the blood and cardiovascular system resulting in cardiac disorders and the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. Exposure at high levels may result in death. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
This substance is possibly carcinogenic to humans.

PHYSICAL
PROPERTIES

Boiling point: 67°C
Relative density (water = 1): 0.87
Solubility in water: very poor
Vapour pressure, kPa at 20°C: 1.3
Relative vapour density (air = 1): 3.56
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.19
Flash point: -21°C
Explosive limits, vol% in air: 1.2 - 26.9

ENVIRONMENTAL
DATA


N O T E S

Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Transport Emergency Card: TEC (R)-30GTF1-III
Card has been partially updated in March 2008: see Packaging & labelling.

ADDITIONAL INFORMATION



ICSC: 1651 ISOBUTYL NITRITE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
 
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