International Chemical Safety Cards METHYLHEXAHYDROPHTHALIC ACID ANHYDRIDE ICSC: 1644 Hexahydromethylphthalic acid anhydride 1,3-Isobenzofurandione, hexahydromethyl- MHHPA C9H12O3 Molecular mass: 168.2 ICSC #    1644 CAS #     25550-51-0 EC #         607-241-00-6 October 11, 2006 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray, foam, powder, carbon dioxide. EXPLOSION EXPOSURE AVOID ALL CONTACT!  •INHALATION Cough. Wheezing. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Face shield and eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Diarrhoea. Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in covered containers. Separated from food and feedstuffs. Dry. Note: C Xn symbol R: 41-42/43 S: 2-22-24-26-37/39 Signal: Danger Health haz May cause allergic or asthmatic symptoms or breathing difficulties if inhaled May cause allergic skin reaction Causes serious eye irritation Causes skin irritation SEE IMPORTANT INFORMATION ON BACK ICSC: 1644 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards METHYLHEXAHYDROPHTHALIC ACID ANHYDRIDE ICSC: 1644 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes slowly on contact with water producing acids. Reacts with acids, alcohols, bases and oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the skin and is severely irritating to the eyes EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma. PHYSICAL PROPERTIES Boiling point: 290°C Melting point: -29°C Density: 1.15 g/cm³ Solubility in water: at 20°C reaction Vapour pressure, Pa at 20°C: 1 Relative density of the vapour/air-mixture at 20°C (air = 1): 5.81 Flash point: 145°C ENVIRONMENTAL DATA N O T E S The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. ADDITIONAL INFORMATION ICSC: 1644 METHYLHEXAHYDROPHTHALIC ACID ANHYDRIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.