International Chemical Safety Cards

CYCLOHEXANEDICARBOXYLIC ACID ANHYDRIDE ICSC: 1643
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
1,3-Isobenzofurandione, hexahydro-
Cyclohexane-1,2-dicarboxylic acid anhydride
Hexahydro-isobenzofuran-1,3-dione
Hexahydrophthalic anhydride
HHPA
C8H10O3
Molecular mass: 154.2
ICSC #    1643
CAS #     85-42-7
EC #         607-102-00-X
November 10, 2006 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
water in large amounts,
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!

 •INHALATION Cough. Wheezing. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Refer for medical attention.
 •SKIN Redness.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
 •EYES Redness. Pain.
Face shield and eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Sore throat. Burning sensation. Abdominal pain. Diarrhoea.
Do not eat, drink, or smoke during work.
Rinse mouth. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Sweep spilled substance into covered containers. Do NOT let this chemical enter the environment.
Dry. Store in an area without drain or sewer access.

Note: C
Xn symbol
R: 41-42/43
S: 2-23-24-26-37/39
Signal: Danger
Health haz
May cause allergic or asthmatic symptoms or breathing difficulties if inhaled
May cause allergic skin reaction
Causes serious eye irritation
Causes skin irritation
Harmful to aquatic life
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1643 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

CYCLOHEXANEDICARBOXYLIC ACID ANHYDRIDE ICSC: 1643
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PHYSICAL STATE; APPEARANCE:
SOLID IN VARIOUS FORMS .

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes slowly on contact with water producing acids.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: (Inhalable fraction & vapour) 0.005 mg/m (Ceiling value); SEN (ACGIH 2008).
MAK: sensitization of respiratory tract (Sa); (DFG 2008).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation.

INHALATION RISK:
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered .

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the skin and is severely irritating to the eyes

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation exposure may cause asthma.
PHYSICAL
PROPERTIES
Boiling point: 296C
Melting point: 35-36C
Solubility in water: reaction
Vapour pressure, Pa at 25C: 0.9
Relative vapour density (air = 1): 5.3
Octanol/water partition coefficient as log Pow: 21.4
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is harmful to aquatic organisms.
N O T E S
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Card has been partially updated in November 2008: see Occupational Exposure Limits, GHS classification.
ADDITIONAL INFORMATION


ICSC: 1643 CYCLOHEXANEDICARBOXYLIC ACID ANHYDRIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.