International Chemical Safety Cards

1-CHLORO-3-NITROBENZENE ICSC: 1633
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Benzene, 1-chloro-3-nitro-
m-Chloronitrobenzene
ClC6H4NO2
Molecular mass: 157.6
6 Poison placard ICSC #    1633
CAS #     121-73-3
RTECS # CZ0940000
UN #        1578
April 19, 2007 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray , foam , carbon dioxide .
EXPLOSION Finely dispersed particles form explosive mixtures in air.


EXPOSURE
PREVENT DISPERSION OF DUST! STRICT HYGIENE!

 •INHALATION Blue lips or finger nails. Dizziness. Headache. Nausea. Confusion. Convulsions.
Local exhaust. Breathing protection.
Fresh air, rest. Refer for medical attention. See Notes.
 •SKIN MAY BE ABSORBED! (see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell
 •EYES Redness.
Safety goggles .
Rinse with plenty of water (remove contact lenses if easily possible).
 •INGESTION Blue skin. (See Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Refer immediately for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Sweep spilled substance into sealablecontainers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.
Separated from combustible and reducing substances, food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Do not transport with food and feedstuffs.
UN Hazard Class: 6.1
UN Packing Group: II
Signal: Danger
Skull-Health haz
Harmful if swallowed
Toxic in contact with skin
Toxic to aquatic life
Causes damage to blood
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1633 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

1-CHLORO-3-NITROBENZENE ICSC: 1633
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PHYSICAL STATE; APPEARANCE:
PALE-YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The substance decomposes on burning, producing toxic and corrosive fumes including nitrogen oxides , chlorine (See ICSC 0126) , hydrogen chloride (see ICSC0163) , and phosgene (See ICSC 0007) , causing fire and explosion hazard. The substance is a strong oxidant and reacts with combustible and reducing materials.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: IIb (not established but data is available) skin absorption (H); (DFG 2008).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is mildly irritating to the eyes. The substance may cause effects on the blood, resulting in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the blood, resulting in the formation of methaemoglobin.
PHYSICAL
PROPERTIES
Boiling point: 236C
Melting point: 44C
Density: 1.3
g/cm
Solubility in water, g/100 ml at 20C:
(very poor)
Vapour pressure, Pa at 20C: 5
Relative vapour density (air = 1): 5.44
Flashpoint: 103C c.c.
Auto-ignition temperature: 500C
Octanol/water partition coefficient as log Pow: 2.41
ENVIRONMENTAL
DATA
Environmental Hazard placard The substance is toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment.
N O T E S
TLV (as para-nitrochlorobenzene): 0.1 ppm (skin) A3 (confirmed animal carcinogen with unknown relevance to humans) BEI issued (ACGIH 2006). See ICSC0028. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Rinse contaminated clothes with plenty of water because of fire hazard.
Transport Emergency Card: TEC (R)-61GT2-II and 61S1578

NFPA Code: H2; F1; R; 0
ADDITIONAL INFORMATION


ICSC: 1633 1-CHLORO-3-NITROBENZENE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.