International Chemical Safety Cards DIPHOSGENE ICSC: 1630 Formic acid, trichloro-methyl ester Trichloromethyl chloroformate ClCOOCCl3 Molecular mass: 197.83 ICSC #    1630 CAS #     503-38-8 RTECS # LQ7350000 April 19, 2007 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. In case of fire in the surroundings: use appropriate extinguishing media. EXPLOSION EXPOSURE STRICT HYGIENE!  •INHALATION Burning sensation. Tightness in the chest. Sore throat. Cough. Laboured breathing. Shortness of breath. Symptoms may be delayed (see Notes). Breathing protection. Closed system and ventilation. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Redness. Protective gloves. Rinse and then wash skin with water and soap.  •EYES Causes watering of the eyes. Redness. Safety goggles . First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Sore throat. Do not eat, drink, or smoke during work. Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: Chemical protection suit including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Dry. Well closed. Keep in a well-ventilated room. Signal: Danger Skull Fatal if inhaled vapour May cause respiratory irritation SEE IMPORTANT INFORMATION ON BACK ICSC: 1630 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards DIPHOSGENE ICSC: 1630 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The vapour is heavier than air . CHEMICAL DANGERS: The substance decomposes on heating producing toxic and corrosive fumes, including chlorine and phosgene. Reacts with water to produce toxic and corrosive fumes. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body in hazardous amounts by inhalation. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the respiratory tract, the skin and the eyes. Lachrymation. Inhalation of this substance may cause lung oedema (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point at 101.3 kPa: 128°C Melting point: -57°C Density: 1.6 g/cm³ Solubility in water: (reaction) Vapour pressure, kPa at 20°C: 1.3 Relative vapour density (air = 1): 6.83 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.08 Octanol/water partition coefficient as log Pow: 1.49 ENVIRONMENTAL DATA N O T E S The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. See Phosgene ICSC0007. ADDITIONAL INFORMATION ICSC: 1630 DIPHOSGENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.