International Chemical Safety Cards 2,4-XYLIDINE ICSC: 1562 2,4-Dimethylaniline 2,4-Dimethylbenzeneamine 1-Amino-2,4-dimethylbenzene 4-Amino-1,3-dimethylbenzene 4-Amino-m-xylene 4-Amino-1,3-xylene C8H11N / (CH3)2C6H3NH2 Molecular mass: 121.2 ICSC #    1562 CAS #     95-68-1 RTECS # ZE8925000 UN #        1711 EC #         612-027-00-0 April 19, 2007 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray, carbon dioxide , foam , powder . EXPLOSION Above 90°C explosive vapour/air mixtures may be formed. Above 90°C use a closed system, ventilation. EXPOSURE STRICT HYGIENE!  •INHALATION Dizziness. Drowsiness. Headache. Nausea. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! Redness. (See Ingestion) Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Blue lips or fingernails. Blue skin. Dizziness. Drowsiness. Headache. Nausea. Unconsciousness. Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Chemical protection suit. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Separated from strong oxidants, acids, acid anhydrides, acid chlorides, hypochlorites, halogens, food and feedstuffs . Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. Do not transport with food and feedstuffs. Note: C T symbol N symbol R: 23/24/25-33-51/53 S: 1/2-28-36/37-45-61 UN Hazard Class: 6.1 UN Packing Group: II Signal: Warning Excl mark-Health haz Harmful if swallowed Causes mild skin irritation Causes eye irritation May cause drowsiness or dizziness May cause damage to blood May cause damage to blood, liver and kidney through prolonged or repeated exposure Toxic to aquatic life SEE IMPORTANT INFORMATION ON BACK ICSC: 1562 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2,4-XYLIDINE ICSC: 1562 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: CLEAR, PALE YELLOW LIQUID , WITH CHARACTERISTIC ODOUR. TURNS REDDISH TO BROWN ON EXPOSURE TO AIR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes including nitrogen oxides . Reacts violently with strong oxidants. Reacts with hypochlorites forming explosive chloroamines. Reacts with acids , acid anhydrides , acid chlorides and halogens . Attacks plastic and rubber. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. See Notes. MAK: Skin absorption (H); Carcinogen category: 2; (DFG 2006). ROUTES OF EXPOSURE: The substance can be absorbed into the body in hazardous amounts by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and is mildly irritating to the skin . Exposure at high levels could cause lowering of consciousness. Exposure at high levels may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood , resulting in anaemia . The substance may have effects on the kidneys and liver . 3, MAK group 2, repeated dose rats: higher concentrations: liver cell necrosis; inhibition of DNA synthesis in the testes of mice; genotoxicity: majority of in vitro genotox tests is positive (ames, chromosome aberration, DNA repair) after metabolic activation PHYSICAL PROPERTIES Boiling point: 214°C Melting point: -16°C Relative density (water = 1): 0.97 Solubility in water, g/100 ml at 20°C: 0.5 Vapour pressure, Pa at 20°C: 11 Relative vapour density (air = 1): 4.19 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00 Flash point: 90°C Auto-ignition temperature: 520°C Explosive limits, vol% in air: 1.1-7.0 Octanol/water partition coefficient as log Pow: 1.68 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. It is strongly advised that this substance does not enter the environment. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. TLV only established for mixed isomers, see ICSC 0600. See also ICSC 0600 (Xylidine, mixed isomers), 1519 (2,6-Xylidine), 0451 (2,3-Xylidine), 0453 (3,4-Xylidine), 1686 (2,5-Xylidine), 1687 (3,5-Xylidine). Transport Emergency Card: TEC (R)-61S1711-L NFPA Code: H3; F1; R0 Card has been partially updated in January 2008: see GHS classification. ADDITIONAL INFORMATION ICSC: 1562 2,4-XYLIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.