International Chemical Safety Cards

GLYCOLONITRILE ICSC: 1427
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
Formaldehyde cyanohydrin
Hydroxyacetonitrile
Cyanomethanol
Glyconitrile
Glycolic acid nitrile solution
C2H3NO / HOCH2CN
Molecular mass: 57.1
6 Poison placard ICSC #    1427
CAS #     107-16-4
RTECS # AM0350000
UN #        3276
September 10, 2002 Validated
L, October 2001 (not reviewed); postponed in Montreal 2002 for long-term effects.
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible.
NO open flames.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION


EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
 •INHALATION Dizziness. Dullness. Headache. Shortness of breath. Weakness. Blue lips or finger nails.
Closed system and ventilation.
Fresh air, rest. No mouth-to-mouth artificial respiration. Refer for medical attention. See Notes.
 •SKIN MAY BE ABSORBED! (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
 •EYES MAY BE ABSORBED! Redness. Pain. Blurred vision. (Further see Inhalation).
Face shield, or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION (See Inhalation).
Do not eat, drink, or smoke during work.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. See Notes.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Wash away remainder with plenty of water. Do NOT let this chemical enter the environment. (Extra personal protection: complete protective clothing including self-contained breathing apparatus.)
Separated from food and feedstuffs , acids, bases . Cool. Store only if stabilized.
Do not transport with food and feedstuffs.
UN Hazard Class: 6.1
UN Packing Group: II
SEE IMPORTANT INFORMATION ON BACK
ICSC: 1427 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

GLYCOLONITRILE ICSC: 1427
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PHYSICAL STATE; APPEARANCE:
COLOURLESS OILY LIQUID

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance may polymerize violently under the influence of traces of acid(s) or base(s) with fire or explosion hazard. The substance decomposes on heating producing toxic fumes including hydrogen cyanide and nitrogen oxides .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
OSHA PEL: none
NIOSH REL: C 2 ppm (5 mg/m3) 15-minute
NIOSH IDLH: N.D. See: IDLH INDEX


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes . The substance may cause effects on the cellular respiration , resulting in convulsions and respiratory failure . Exposure may result in death. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
The substance may have effects on the nervous system and thyroid .
PHYSICAL
PROPERTIES
Boiling point: 183C
Melting point: -72C
Relative density (water = 1): 1.1
Solubility in water: good
Vapour pressure, Pa at 63C: 100
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20C (air = 1): 1.00
Octanol/water partition coefficient as log Pow: -1.6
ENVIRONMENTAL
DATA
Environmental Hazard placard This substance may be hazardous in the environment; special attention should be given to aquatic organisms.
N O T E S
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Commercial products are supplied as stabilized 70 % solutions in water.
Transport Emergency Card: TEC (R)-61GT1-I
ADDITIONAL INFORMATION


ICSC: 1427 GLYCOLONITRILE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.