International Chemical Safety Cards 4-NITROBIPHENYL ICSC: 1395 p-Nitrobiphenyl p-Nitrodiphenyl C12H9NO2 Molecular mass: 199.2 ICSC #    1395 CAS #     92-93-3 RTECS # DV5600000 EC #         609-039-00-3 July 03, 2002 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID ALL CONTACT!  •INHALATION See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE. See Notes. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Safety spectacles or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. Personal protection: P3 filter respirator for toxic particles. Separated from strong reducing agents . Well closed. T symbol N symbol R: 45-51/53 S: 53-45-61 SEE IMPORTANT INFORMATION ON BACK ICSC: 1395 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 4-NITROBIPHENYL ICSC: 1395 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: WHITE TO YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic gases . Reacts with strong reducing agents causing toxic hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: (skin); A2 (suspected human carcinogen); (ACGIH 2004). MAK: skin absorption (H); Carcinogen category: 2; (DFG 2004). OSHA PEL: 1910.1003 See Appendix B NIOSH REL: Ca See Appendix A NIOSH IDLH: Ca N.D. See: IDLH INDEX ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: This substance is probably carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 340°C Melting point: 114°C Solubility in water: very poor Flash point: 143°C c.c. Octanol/water partition coefficient as log Pow: 3.77 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. The substance may cause long-term effects in the aquatic environment. N O T E S Similar substances have caused methemoglobinemia, but there are no data available for this substance. Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. Card has been partly updated in April 2005. See section Occupational Exposure Limits. ADDITIONAL INFORMATION ICSC: 1395 4-NITROBIPHENYL (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.