International Chemical Safety Cards 2,3,4,6-TETRACHLOROPHENOL ICSC: 1089 2,4,5,6-Tetrachlorophenol Phenol, 2,3,4,6-tetrachloro- C6H2Cl4O Molecular mass: 231.9 ICSC #    1089 CAS #     58-90-2 RTECS # SM9275000 UN #        2020 EC #         604-013-00-8 October 20, 2005 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray. Alcohol-resistant foam. Dry powder. Carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION Cough. Shortness of breath. Convulsions. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Safety goggles . First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Diarrhoea. Headache. Dizziness. Vomiting. Weakness. Convulsions. Muscular spasms. Increased body temperature and sweating (see Notes). Do not eat, drink, or smoke during work. Wash hands before eating. Give a slurry of activated charcoal in water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Personal protection: P2 filter respirator for harmful particles. Chemical protection suit. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs . Store in an area without drain or sewer access. Do not transport with food and feedstuffs. T symbol N symbol R: 25-36/38-50/53 S: 1/2-26-28-37-45-60-61 UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 1089 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2,3,4,6-TETRACHLOROPHENOL ICSC: 1089 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: BROWN SOLID IN VARIOUS FORMS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing corrosive fumes including hydrogen chloride . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful concentration of airborne particles can be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . See Notes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver . The substance may have effects on the skin , resulting in chloracne. (See Notes.) PHYSICAL PROPERTIES Melting point: 70°C Density: 1.8 g/cm³ Solubility in water, g/100 ml at 20°C: 0.1 (very poor) Flash point: 100°C Octanol/water partition coefficient as log Pow: 4.45 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. N O T E S 2,3,4,6-Tetrachlorophenol is a polychlorophenol which, as a group, has been classified by IARC (1999) as possibly carcinogenic to humans, but the data on this specific substance are inconclusive. No data are available on this isomer but a mixture of tetrachlorophenols may cause irritation of the skin, eyes and respiratory tract. These substances may cause acute metabolic effects resulting in damage in several organs notably in central nervous system. Some technical products may contain highly toxic impurities including polychlorinated dibenzo-p-dioxins and -furans. Depending on the degree of exposure, periodic medical examination is suggested. Transport Emergency Card: TEC (R)-61S2020 or 61GT2-III ADDITIONAL INFORMATION ICSC: 1089 2,3,4,6-TETRACHLOROPHENOL (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.