International Chemical Safety Cards

MALEIC ANHYDRIDE ICSC: 0799
World Health Organization (WHO) International Labour Organization (ILO) United Nations Environmental Programme (UNEP) European Commission National Institute for Occupational Safety and Health (NIOSH)
2,5-Furandione
Dihydro-2,5-dioxofuran
Maleic acid anhydride
cis-Butenedioic anhydride
C4H2O3
Molecular mass: 98.1
8 Corrosive placard ICSC #    0799
CAS #     108-31-6
RTECS # ON3675000
UN #        2215
EC #         607-096-00-9
September 10, 1997 Validated
TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/
FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, alcohol-resistant foam, carbon dioxide, NO powder.
EXPLOSION Finely dispersed particles form explosive mixtures in air.


EXPOSURE
STRICT HYGIENE!

 •INHALATION Sore throat. Cough. Burning sensation. Shortness of breath.
Local exhaust or breathing protection.
Fresh air, rest. Half-upright position. Refer for medical attention.
 •SKIN Redness. Pain.
Protective gloves. Protective clothing.
First rinse with plenty of water, then remove contaminated clothes and rinse again.
 •EYES Redness. Pain.
Safety goggles, or eye protection in combination with breathing protection if powder.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
 •INGESTION Abdominal pain. Burning sensation.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.
SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING
Sweep spilled substance into coveredcontainers. Chemical protection suit. Use face shield. Personal protection: P3 filter respirator for toxic particles.
Separated from strong oxidants, strong bases, food and feedstuffs. Dry.
Do not transport with food and feedstuffs.
C symbol
R: 22-34-42/43
S: 2-22-26-36/37/39-45
UN Hazard Class: 8
UN Packing Group: III
SEE IMPORTANT INFORMATION ON BACK
ICSC: 0799 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

MALEIC ANHYDRIDE ICSC: 0799
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PHYSICAL STATE; APPEARANCE:
COLOURLESS OR WHITE CRYSTALS , WITH PUNGENT ODOUR.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on contact with water producing corrosive maleic acid. The solution in water is a medium strong acid. Reacts with strong oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.1 mg/m³ as TWA A4 (not classifiable as a human carcinogen); SEN (ACGIH 2005).
MAK: 0.1 ppm 0.41 mg/m³ sensitization of respiratory tract and skin (Sah);
Peak limitation category: I (1) Pregnancy risk group: C
(DFG 2005).
OSHA PEL: TWA 1 mg/m3 (0.25 ppm)
NIOSH REL: TWA 1 mg/m3 (0.25 ppm)
NIOSH IDLH: 10 mg/m3 See: 108316


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance irritates severely the eyes, the skin and the respiratory tract. Inhalation of the substance may cause asthma-like reactions.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged inhalation exposure may cause asthma. The substance may have effects on the eyes , resulting in chronic eyes irritation.
PHYSICAL
PROPERTIES
Boiling point: 202°C
Melting point: 53°C
Density: 1.5
Solubility in water: reaction
Vapour pressure, Pa at 25°C: 25
Relative vapour density (air = 1): 3.4
Flash point: 102°C c.c.
Auto-ignition temperature: 477°C
Explosive limits, vol% in air: 1.4-7.1
ENVIRONMENTAL
DATA

N O T E S
Reacts violently with fire extinguishing agents such as powder. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. The odour warning when the exposure limit value is exceeded is insufficient.
Transport Emergency Card: TEC (R)-80S2215-S
NFPA Code: H3; F1; R1;
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ADDITIONAL INFORMATION


ICSC: 0799 MALEIC ANHYDRIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.