International Chemical Safety Cards THIRAM ICSC: 0757 Tetramethylthiuram disulfide Bis (dimethylthiocarbamoyl) disulfide TMTD Tetramethylthioperoxydicarbonic diamide (((H2N)C(S))2S2) C6H12N2S4 / (CH3)2NCSSSCSN(CH3)2 Molecular mass: 240.4 ICSC #    0757 CAS #     137-26-8 RTECS # JO1400000 UN #        3077 EC #         006-005-00-4 December 04, 2000 Validated TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. EXPOSURE AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!  •INHALATION Confusion. Cough. Dizziness. Headache. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety spectacles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (See Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Separated from acids, strong oxidants, food and feedstuffs . Dry. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Marine pollutant. Xn symbol N symbol R: 20/22-36/38-43-48/22-50/53 S: 2-26-36/37-60-61 UN Hazard Class: 9 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0757 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards THIRAM ICSC: 0757 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALS. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. CHEMICAL DANGERS: The substance decomposes on burning, producing toxic fumes including sulfur oxides and carbon sulfide. Reacts with strong oxidants, acids and oxidizable materials. OCCUPATIONAL EXPOSURE LIMITS: TLV: 1 mg/m³ as TWA; A4; (ACGIH 2004). MAK: (Inhalable fraction) 1 mg/m³; sensitization of skin (Sh); Peak limitation category: II(2); Pregnancy risk group: C; (DFG 2006). OSHA PEL: TWA 5 mg/m3 NIOSH REL: TWA 5 mg/m3 NIOSH IDLH: 100 mg/m3 See: 137268 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the thyroid , liver . PHYSICAL PROPERTIES Boiling point at 2.6 kPa: (see Notes) 129°C Melting point: (see Notes) 155-156°C Density: 1.3 g/cm³ Solubility in water: none Vapour pressure, Pa at 20°C: negligible Flash point: 89°C c.c. (see Notes) Octanol/water partition coefficient as log Pow: 1.82 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. N O T E S Physical properties reported in literature are inconsistent. Carrier solvents used in commercial formulations may change physical and toxicological properties. Use of alcoholic beverages enhances the harmful effect. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Card has been partly updated in October 2004 & 2006. See sections: EU classification, Emergency Response, Occupational Exposure Limits. Transport Emergency Card: TEC (R)-90GM7-III ADDITIONAL INFORMATION ICSC: 0757 THIRAM (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.